Etienne Sollier, Anna Riedel, Umut H. Toprak, Justyna A. Wierzbinska, Dieter Weichenhan, Jan Philipp Schmid, Mariam Hakobyan, Aurore Touzart, Ekaterina Jahn, Binje Vick, Fiona Brown-Burke, Katherine Kelly, Simge Kelekci, Anastasija Pejkovska, Ashish Goyal, Marion B?hr, Kersten Breuer, Mei-Ju May Chen, Maria Llamazares-Prada, Mark Hartmann, Maximilian Sch?nung, Nadia Correia, Andreas Trumpp, Yomn Abdullah, Ursula Klingmüller, Sadaf S. Mughal, Benedikt Brors, Frank Westermann, Elias Ulrich, Robert J. Autry, Matthias Schlesner, Sebastian Vosberg, Tobias Herold, Philipp A. Greif, Dietmar Pfeifer, Michael Lübbert, Thomas Fischer, Florian H. Heidel, Claudia Gebhard, Wencke Walter, Torsten Haferlach, Ann-Kathrin Eisfeld, Krzysztof Mrózek, Deedra Nicolet, Lars Bullinger, Leonie Smeenk, Claudia Erpelinck-Verschueren, Roger Mulet-Lazaro, Ruud Delwel, Aurélie Ernst, Michael Scherer, Pavlo Lutsik, Irmela Jeremias, Konstanze D?hner, Hartmut D?hner, Daniel B. Lipka and Christoph Plass. in press. Enhancer hijacking discovery in acute myeloid leukemia by pyjacker identifies MNX1 activation via deletion 7q. Blood Cancer Discovery . DOI: 10.1158/2643-3230.bcd-24-0278
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Areeba Patel, Kirsten G?bel, Sebastian Ille, Felix Hinz, Natalie Schoebe, Henri Bogumil, Jochen Meyer, Michelle Brehm, Helin Kardo, Daniel Schrimpf, Artem Lomakin, Michael Ritter, Pauline G?ller, Paul Kerbs, Lisa Pfeifer, Stefan Hamelmann, Christina Blume, Franziska M. Ippen, Natalie Berghaus, Philipp Euskirchen, Leonille Schweizer, Claus Hultschig, Nadine Van Roy, Jo Van Dorpe, Joni Van der Meulen, Siebe Loontiens, Franceska Dedeurwaerdere, Henning Leske, Skarphé?inn Halldórsson, Graeme Fox, Simon Deacon, Inswasti Cahyani, Nadine Holmes, Satrio Wibowo, Rory Munro, Dan Martin, Abid Sharif, Mark Housley, Robert Goldspring, Sebastian Brandner, Somak Roy, Jürgen Hench, Stephan Frank, Andreas Unterberg, Violaine Goidts, Natalie J?ger, Simon Paine, Stuart Smith, Christel Herold-Mende, Wolfgang Wick, Stefan M. Pfister, Einar O. Vik-Mo, Andreas von Deimling, Sandro Krieg, David T. W. Jones, Matthew Loose, Matthias Schlesner, Martin Sill and Felix Sahm. in press. Prospective, multicenter validation of a platform for rapid molecular profiling of central nervous system tumors. Nature 伟德国际_伟德国际1946$娱乐app游戏icine . DOI: 10.1038/s41591-025-03562-5
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Teng-Feng Li, Paul Rothhaar, Arthur Lang, Oliver Grünvogel, Ombretta Colasanti, Santa Mariela Olivera Ugarte, Jannik Traut, Antonio Piras, Nelson Acosta-Rivero, Vladimir Gon?alves Magalh?es, Emely Springer, Andreas Betz, Hao-En Huang, Jeongbin Park, Ruiyue Qiu, Gnimah Eva Gnouamozi, Ann-Kathrin Mehnert, Viet Loan Dao Thi, Stephan Urban, Martina Muckenthaler, Matthias Schlesner, Dirk Wohlleber, Marco Binder, Ralf Bartenschlager, Andreas Pichlmair and Volker Lohmann. 2025. RBM39 shapes innate immunity by controlling the expression of key factors of the interferon response. Frontiers in Immunology 16, 1568056. DOI: 10.3389/fimmu.2025.1568056
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Andreas Betz, Hao-En Huang, Zuguang Gu, Ombretta Colasanti, Teng-Feng Li, Jasper Hesebeck-Brinckmann, Nadine Gillich, Gnimah Eva Gnouamozi, Matthias Schlesner, Florian W. R. Vondran, Stephan Urban, Ralf Bartenschlager, Marco Binder and Volker Lohmann. in press. Reconstitution of interferon regulatory factor 7 expression restores interferon beta induction in Huh7 cells. Journal of Virology e00703-25. DOI: 10.1128/jvi.00703-25
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Selina Glaser, Anja Fischer, Juan Emilio Martínez-Manjón, Cristina López, Helene Kretzmer, Birgit Burkhardt, Daniel Hübschmann, Michael Hummel, Wolfram Klapper, Julia Kolarova, Markus Kreuz, German Ott, Bernhard Radlwimmer, Maciej Rosolowski, Matthias Schlesner, Andreas Rosenwald, Stephan Stilgenbauer, Rabea Wagener, Igor Zwir, Lorenz Trümper, Ralf Küppers, Peter Lichter, Ole Ammerpohl, Coral del Val and Reiner Siebert. in press. Subgrouping germinal center-derived B-cell lymphomas based on machine learning-deduced DNA methylation modules [Letter]. Leukemia . DOI: 10.1038/s41375-025-02533-6
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Selina Glaser, Rabea Wagener, Helene Kretzmer, Cristina López, Maria Joao Baptista, Susanne Bens, Stephan Bernhart, Kishor Bhatia, Arndt Borkhardt, Shaymaa Elgaafary, Steve Hoffmann, Daniel Hübschmann, Michael Hummel, Wolfram Klapper, Julia Kolarova, Markus Kreuz, Stefano Lazzi, Markus L?ffler, Jose Tomas Navarro, Janet Neequaye, Noel Onyango, Timothy Onyuma, German Ott, Bernhard Radlwimmer, Marius Rohde, Andreas Rosenwald, Maciej Rosolowski, Matthias Schlesner, Monika Szczepanowski, Gustavo Tapia, Wilhelm W??mann, Ralf Küppers, Lorenz Trümper, Lorenzo Leoncini, Peter Lichter, Coral del Val, Ole Ammerpohl, Birgit Burkhardt, Sam M. Mbulaiteye and Reiner Siebert. 2025. Subtyping Burkitt lymphoma by DNA methylation. Genes, Chromosomes & Cancer 64, 4, e70042. DOI: 10.1002/gcc.70042
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Anagh A. Sahasrabuddhe, Xiaofei Chen, Kaiyu Ma, Rui Wu, Huan-Chang Liang, Richa Kapoor, Rishi R. Chhipa, Ozlem Onder, Courtney McFetridge, John S. Van Arnam, Xiao Zhang, Jennifer J. D. Morrissette, Vinodh Pillai, Marilyn M. Li, Philippe Szankasi, Venkatesha Basrur, Kevin P. Conlon, Tobias D. Raabe, Nathanael G. Bailey, Cory M. Hogaboam, Robert Rottapel, Junhyong Kim, Cristina López, Matthias Schlesner, Reiner Siebert, Kostiantyn Dreval, Ryan D. Morin, Loredana Moro, Michele Pagano, Louis M. Staudt, Megan S. Lim and Kojo S. J. Elenitoba-Johnson. 2025. The FBXO45-GEF-H1 axis controls germinal center formation and B-cell lymphomagenesis. Cancer Discovery 15, 4, 838-861. DOI: 10.1158/2159-8290.cd-24-0442
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Stephanie Gehrs, Moritz Jakab, Ewgenija Gutjahr, Zuguang Gu, Dieter Weichenhan, Jan-Philipp Mallm, Carolin Mogler, Matthias Schlesner, Christoph Plass, Katharina Schlereth and Hellmut G. Augustin. in press. The spatial zonation of the murine placental vasculature is specified by epigenetic mechanisms. Developmental Cell . DOI: 10.1016/j.devcel.2024.12.037
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Ling Hai, Dirk C. Hoffmann, Robin J. Wagener, Daniel D. Azorin, David Hausmann, Ruifan Xie, Magnus-Carsten Huppertz, Julien Hiblot, Philipp Sievers, Sophie Heuer, Jakob Ito, Gina Cebulla, Alexandros Kourtesakis, Leon D. Kaulen, Miriam Ratliff, Henriette Mandelbaum, Erik Jung, Ammar Jabali, Sandra Horschitz, Kati J. Ernst, Denise Reibold, Uwe Warnken, Varun Venkataramani, Rainer Will, Mario L. Suvà, Christel Herold-Mende, Felix Sahm, Frank Winkler, Matthias Schlesner, Wolfgang Wick and Tobias Kessler. 2024. A clinically applicable connectivity signature for glioblastoma includes the tumor network driver CHI3L1. Nature Communications 15, 1, 968. DOI: 10.1038/s41467-024-45067-8
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Victoria Fincke, Maurice Lossner, Irmengard Sax, Marlena Mucha, Felix Dorn, Stefan Wudy, Christian Vokuhl, Rainer Claus, Marina Kunstreich, Christoph Slavetinsky, Jorg Fuchs, Matthias Schlesner, Michael Frühwald, Antje Redlich, Michaela Kuhlen and Pascal Johann. 2024. Analysis of DNA methylation profiles and single nuclei RNA-seq of pediatric adrenocortical tumors reveal subgroups of clinical relevance and distinct tumor biology [Abstract]. Endocrine Abstracts 99, EP27. DOI: 10.1530/endoabs.99.ep27
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Victoria E. Fincke, Mona Steinbügl, Hye-Jung E. Chun, Karolina Nemes, Marlena Mucha, Maurice Lo?ner, Felix Dorn, Katharina Gastberger, Sebastian Bühner, Martin Sill, Thomas Kr?ncke, Reiner Siebert, Patrick Melchior, Rhoikos Furtw?ngler, Matthias Schlesner, Christian Vokuhl, Christoph R?cken, Pascal D. Johann and Michael C. Frühwald. 2024. Clinical and molecular risk factors in extracranial malignant rhabdoid tumors: toward an integrated model of high-risk tumors. Clinical Cancer Research 30, 20, 4667-4680. DOI: 10.1158/1078-0432.ccr-23-3489
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Sebastian Sommer, Maximilian Schmutz, Kathrin Hildebrand, Annett Schiwitza, Selinah Benedikt, Maria Eberle, Tatiana M?gele, Aziz Sultan, Lena Reichl, Maria Campillo, Luise Uhrmacher, Ana Antic Nikolic, Ralph Bundschuh, Constantin Lapa, Michaela Kuhlen, Sebastian Dintner, Angela Langer, Bruno M?rkl, Thomas Wendler, Kartikay Tehlan, Thomas Kr?ncke, Maria Wahle, Matthias Mann, Nicolas Casadei, Michaela Pogoda, Simone Hummler, Irmengard Sax, Matthias Schlesner, Boris Kubuschok, Martin Trepel and Rainer Claus. 2024. Concept and feasibility of the Augsburg Longitudinal Plasma Study (ALPS) - a prospective trial for comprehensive liquid biopsy-based longitudinal monitoring of solid cancer patients. Journal of Laboratory 伟德国际_伟德国际1946$娱乐app游戏icine 48, 3, 107-119. DOI: 10.1515/labmed-2023-0156
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Philipp A. Toussaint, Florian Leiser, Scott Thiebes, Matthias Schlesner, Benedikt Brors and Ali Sunyaev. 2024. Explainable artificial intelligence for omics data: a systematic mapping study. Briefings in Bioinformatics 25, 1, bbad453. DOI: 10.1093/bib/bbad453
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Selina Glaser, Helene Kretzmer, Iris?Tatjana Kolassa, Matthias Schlesner, Anja Fischer, Isabell Fenske, Reiner Siebert and Ole Ammerpohl. 2024. Navigating Illumina DNA methylation data: biology versus technical artefacts. NAR Genomics and Bioinformatics 6, 4, lqae181. DOI: 10.1093/nargab/lqae181
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Areeba J. Patel, Kirsten G?bel, Felix Hinz, Helin Dogan, Daniel Schrimpf, Pauline G?ller, Henning Leske, Skarphé?inn Halldórsson, Graeme Fox, Simon Deacon, Simon Paine, Stuart Smith, Natalie J?ger, Christel Herold-Mende, Wolfgang Wick, Stefan M. Pfister, Einar Vik-Mo, Andreas von Deimling, Matthias Schlesner, David T. W. Jones, Matthew Loose, Martin Sill and Felix Sahm. 2024. PATH-10. Accelerating comprehensive CNS tumor molecular diagnostics with Rapid-CNS2 and MNP-flex: a prospective multi-center validation [Abstract]. Neuro-Oncology 26, Supplement 4, iv204. DOI: 10.1093/neuonc/noae064.713
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Sophie Heuer, Ina Burghaus, Maria Gose, Tobias Kessler, Felix Sahm, Philipp Vollmuth, Varun Venkataramani, Dirk Hoffmann, Matthias Schlesner, Miriam Ratliff, Carsten Hopf, Ulrich Herrlinger, Franz Ricklefs, Martin Bendszus, Sandro M. Krieg, Antje Wick, Wolfgang Wick and Frank Winkler. 2024. PerSurge (NOA-30) phase II trial of perampanel treatment around surgery in patients with progressive glioblastoma. BMC Cancer 24, 1, 135. DOI: 10.1186/s12885-024-11846-1
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Yu-Yu Lin, Kersten Breuer, Dieter Weichenhan, Pascal Lafrenz, Agata Wilk, Marina Chepeleva, Oliver Mücke, Maximilian Sch?nung, Franziska Petermann, Philipp Kensche, Lena Weiser, Frank Thommen, Gideon Giacomelli, Karl Nordstroem, Edahi Gonzalez-Avalos, Angelika Merkel, Helene Kretzmer, Jonas Fischer, Stephen Kr?mer, Murat Iskar, Stephan Wolf, Ivo Buchhalter, Manel Esteller, Chris Lawerenz, Sven Twardziok, Marc Zapatka, Volker Hovestadt, Matthias Schlesner, Marcel Schulz, Steve Hoffmann, Clarissa Gerhauser, J?rn Walter, Mark Hartmann, Daniel B. Lipka, Yassen Assenov, Christoph Bock, Christoph Plass, Reka Toth and Pavlo Lutsik. in press. Pipeline Olympics: continuable benchmarking of computational workflows for DNA methylation sequencing data against an experimental gold standard. preprint. DOI: 10.1101/2024.09.16.609142
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Etienne Sollier, Anna Riedel, Umut H. Toprak, Justyna A. Wierzbinska, Dieter Weichenhan, Jan Philipp Schmid, Mariam Hakobyan, Aurore Touzart, Ekaterina Jahn, Binje Vick, Fiona Brown-Burke, Katherine Kelly, Simge Kelekci, Anastasija Pejkovska, Ashish Goyal, Marion B?hr, Kersten Breuer, Mei-Ju May Chen, Maria Llamazares-Prada, Mark Hartmann, Maximilian Sch?nung, Nádia Correia, Andreas Trumpp, Yomn Abdullah, Ursula Klingmüller, Sadaf S. Mughal, Benedikt Brors, Frank Westermann, Matthias Schlesner, Sebastian Vosberg, Tobias Herold, Philipp A. Greif, Dietmar Pfeifer, Michael Lübbert, Thomas Fischer, Florian H. Heidel, Claudia Gebhard, Wencke Walter, Torsten Haferlach, Ann-Kathrin Eisfeld, Krzysztof Mrózek, Deedra Nicolet, Lars Bullinger, Leonie Smeenk, Claudia Erpelinck, Roger Mulet-Lazaro, Ruud Delwel, Aurélie Ernst, Michael Scherer, Pavlo Lutsik, Irmela Jeremias, Konstanze D?hner, Hartmut D?hner, Daniel B. Lipka and Christoph Plass. in press. Pyjacker identifies enhancer hijacking events in acute myeloid leukemia including MNX1 activation via deletion 7q. preprint. DOI: 10.1101/2024.09.11.611224
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Areeba Patel, Kirsten G?bel, Felix Hinz, Helin Dogan, Daniel Schrimpf, Pauline G?ller, Henning Leske, Skarpheoinn Halldórsson, Graeme Fox, Simon Deacon, Simon Paine, Stuart Smith, Natalie J?ger, Christel Herold-Mende, Wolfgang Wick, Stefan Pfister, Einar Vik-Mo, Andreas von Deimling, Matthias Schlesner, David T. Jones, Matthew Loose, Martin Sill and Felix Sahm. 2024. Rapid-CNS2 combined with MNP-Flex enables next-day comprehensive molecular diagnostic profiling of CNS tumors in a global cohort [Abstract]. The Journal of Molecular Diagnostics 26, 6, Supplement, S13. DOI: 10.1016/S1525-1578(24)00122-3
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Bianca Grosser, Christian M. Heyer, Johannes Austgen, Eva Sipos, Nic G. Reitsam, Andreas Hauser, Alison VanSchoiack, David Kroeppler, Dmytro Vlasenko, Andreas Probst, Alexander Novotny, Wilko Weichert, Gisela Keller, Matthias Schlesner and Bruno M?rkl. 2024. Stroma AReactive Invasion Front Areas (SARIFA) proves prognostic relevance in gastric carcinoma and is based on a tumor–adipocyte interaction indicating an altered immune response. Gastric Cancer 27, 72-85. DOI: 10.1007/s10120-023-01436-8
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Till Seiboldt, Constantia Zeiser, Duy Nguyen, Simay Celikyürekli, Sonja Herter, Sara Najafi, Alexandra Stroh-Dege, Chris Meulenbroeks, Norman Mack, Rabia Salem-Altintas, Frank Westermann, Matthias Schlesner, Till Milde, Marcel Kool, Tim Holland-Letz, Meike Vogler, Heike Peterziel, Olaf Witt and Ina Oehme. 2024. Synergy of retinoic acid and BH3 mimetics in MYC(N)-driven embryonal nervous system tumours. British Journal of Cancer 131, 4, 763-777. DOI: 10.1038/s41416-024-02740-5
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Sandrine Jayne, Cristina López, Natalie Put, Inga Nagel, Els Lierman, Eva Maria Murga Penas, Lucienne Michaux, Matthew J. Ahearne, Harriet S. Walter, Susanne Bens, Cosima Drewes, Monika Szczepanowski, Matthias Schlesner, Philip Rosenstiel, Iwona Wlodarska, Reiner Siebert and Martin J. S. Dyer. 2024. The chromosomal translocation t(1;6)(p35.3;p25.2), recurrent in chronic lymphocytic leukaemia, leads to RCC1::IRF4 fusion. British Journal of Haematology 205, 6, 2321-2326. DOI: 10.1111/bjh.19790
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Marit M. Grimsrud, Michael Forster, Benjamin Goeppert, Georg Hemmrich-Stanisak, Irmi Sax, Krzysztof Grzyb, Peder R. Braadland, Alphonse Charbel, Carmen Metzger, Thomas Albrecht, Tim Alexander Steiert, Matthias Schlesner, Michael P. Manns, Arndt Vogel, Sheraz Yaqub, Tom H. Karlsen, Peter Schirmacher, Kirsten M. Boberg, Andre Franke, Stephanie Roessler and Trine Folseraas. 2024. Whole-exome sequencing reveals novel cancer genes and actionable targets in biliary tract cancers in primary sclerosing cholangitis. Hepatology Communications 8, 7, e0461. DOI: 10.1097/hc9.0000000000000461
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M. Renner, M. Ole?, N. Paramasivam, A. Schneider, C. E. Heilig, C. Modugno, C. Herremans, A. Mock, D. Lipka, S. Bauer, T. Kindler, C. H. Brandts, U. Keilholz, M. Boerries, B. Kuster, D. Hübschmann, Matthias Schlesner, H. Glimm, R. F. Schlenk and S. Fr?hling. 2023. 1936P Targeted therapy of desmoplastic small round cell tumor guided by multilayered molecular profiling [Abstract]. Annals of Oncology 34, Supplement 2, S1040. DOI: 10.1016/j.annonc.2023.09.1165
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Dirk Hoffmann, Ling Hai, Robin Wagener, David Hausmann, Daniel Domínguez Azorín, Ruifan Xie, Magnus-Carsten Huppertz, Julien Hiblot, Philipp Sievers, Jakob Ito, Sophie Weil, Gina Cebulla, Henriette Mandelbaum, Erik Jung, Alexandros Kourtesakis, Kati Ernst, Denise Reibold, Uwe Warnken, Varun Venkataramani, Rainer Will, Mario Suva, Christel Herold-Mende, Felix Sahm, Frank Winkler, Matthias Schlesner, Wolfgang Wick and Tobias Kessler. 2023. CNSC-09 CHI3L1 is amolecular marker for gliobastoma network connectivity and functionally orchestrates tumor microtube formation [Abstract]. Neuro-Oncology 25, Supplement 5, v24. DOI: 10.1093/neuonc/noad179.0093
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Maximilian Sch?nung, Mark Hartmann, Stephen Kr?mer, Sina St?ble, Mariam Hakobyan, Emely Kleinert, Theo Aurich, Defne Cobanoglu, Florian H. Heidel, Stefan Fr?hling, Michael D. Milsom, Matthias Schlesner, Pavlo Lutsik and Daniel B. Lipka. 2023. Dynamic DNA methylation reveals novel cis-regulatory elements in mouse hematopoiesis. Experimental Hematology 117, 24-42. DOI: 10.1016/j.exphem.2022.11.001
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Yasmeen Niazi, Nagarajan Paramasivam, Joanna Blocka, Abhishek Kumar, Stefanie Huhn, Matthias Schlesner, Niels Weinhold, Rolf Sijmons, Mirjam De Jong, Brian Durie, Hartmut Goldschmidt, Kari Hemminki and Asta F?rsti. 2023. Investigation of rare non-coding variants in familial multiple myeloma. Cells 12, 1, 96. DOI: 10.3390/cells12010096
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Weiyin Zhou, Anja Fischer, Martin D. Ogwang, Wen Luo, Patrick Kerchan, Steven J. Reynolds, Constance N. Tenge, Pamela A. Were, Robert T. Kuremu, Walter N. Wekesa, Nestory Masalu, Esther Kawira, Tobias Kinyera, Isaac Otim, Ismail D. Legason, Hadijah Nabalende, Leona W. Ayers, Kishor Bhatia, James J. Goedert, Mateus H. Gouveia, Nathan Cole, Belynda Hicks, Kristine Jones, Michael Hummel, Matthias Schlesner, George Chagaluka, Nora Mutalima, Eric Borgstein, George N. Liomba, Steve Kamiza, Nyengo Mkandawire, Collins Mitambo, Elizabeth M. Molyneux, Robert Newton, Selina Glaser, Helene Kretzmer, Michelle Manning, Amy Hutchinson, Ann W. Hsing, Yao Tettey, Andrew A. Adjei, Stephen J. Chanock, Reiner Siebert, Meredith Yeager, Ludmila Prokunina-Olsson, Mitchell J. Machiela and Sam M. Mbulaiteye. 2023. Mosaic chromosomal alterations in peripheral blood leukocytes of children in sub-Saharan Africa. Nature Communications 14, 1, 8081. DOI: 10.1038/s41467-023-43881-0
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Mark Hartmann, Maximilian Sch?nung, Jovana Rajak, Joschka Hey, Valentin Maurer, Ling Hai, Sina Staeble, Jens Langstein, Katharina Bauer, Mariam Hakobyan, Laura Jardine, Sheila Bohler, Dominik Vonficht, Abdul-Habib Maag, Dirk Lebrecht, Katrin M. Bernt, Roland Roelz, Tobias Boch, Eleonora Khabirova, Pavlo Lutsik, Simon Haas, Muzlifah Haniffa, Sam Behjati, Jan-Philipp Mallm, Christian Buske, Michael D. Milsom, Stefan Fr?hling, Marc-Jan Bonder, Charlotte Niemeyer, Christian Flotho, Christoph Plass, Miriam Erlacher, Matthias Schlesner and Daniel B. Lipka. 2023. OC 34 - Onco-fetal programming drives high-risk juvenile myelomonocytic leukemia, which can be targeted by anti-CD52 treatment [Abstract]. EJC Paediatric Oncology 2, Supplement 1, 100065. DOI: 10.1016/j.ejcped.2023.100065
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Heike Peterziel, Nora Jamaladdin, Dina ElHarouni, Xenia F. Gerloff, Sonja Herter, Petra Fiesel, Yannick Berker, Mirjam Blattner-Johnson, Kathrin Schramm, Barbara C. Jones, David Reuss, Laura Turunen, Aileen Friedenauer, Tim Holland-Letz, Martin Sill, Lena Weiser, Christopher Previti, Gnanaprakash Balasubramanian, Nicolas U. Gerber, Johannes Gojo, Caroline Hutter, Ingrid ?ra, Olli Lohi, Antonis Kattamis, Bram de Wilde, Frank Westermann, Stephan Tippelt, Norbert Graf, Michaela Nathrath, Monika Sparber-Sauer, Astrid Sehested, Christof M. Kramm, Uta Dirksen, Olli Kallioniemi, Stefan M. Pfister, Cornelis M. van Tilburg, David T. W. Jones, Jani Saarela, Vilja Pieti?inen, Natalie J?ger, Matthias Schlesner, Annette Kopp-Schneider, Sina Oppermann, Till Milde, Olaf Witt and Ina Oehme. 2023. OTHR-04. Development of a functional plattform for real-time personalized drug sensitivity profiling of patient-derived 3D fresh tumor tissue cultures in the pediatric precision oncology program INFORM [Abstract]. Neuro-Oncology 25, Supplement 1, i74-i75. DOI: 10.1093/neuonc/noad073.286
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Mark Hartmann, Maximilian Sch?nung, Jovana Rajak, Valentin Maurer, Ling Hai, Katharina Bauer, Mariam Hakobyan, Sina Staeble, Jens Langstein, Laura Jardine, Roland R?lz, Sheila Bohler, Eleonora Khabirova, Abdul-Habib Maag, Dominik Vonficht, Dirk Lebrecht, Katrin M. Bernt, Kai Tan, Changya Chen, Fatemeh Alikarami, Tobias Boch, Viktoria Flore, Pavlo Lutsik, Michael D. Milsom, Simon Raffel, Christian Buske, Simon Haas, Muzlifah Haniffa, Jan-Philipp Mallm, Sam Behjati, Marc-Jan Bonder, Stefan Fr?hling, Charlotte M. Niemeyer, Joschka Hey, Christian Flotho, Christoph Plass, Miriam Erlacher, Matthias Schlesner and Daniel B. Lipka. in press. Oncogenic RAS-pathway activation drives oncofetal reprogramming and creates therapeutic vulnerabilities in juvenile myelomonocytic leukemia. preprint. DOI: 10.1101/2023.10.27.563754
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Sebastian Sommer, Maximilian Schmutz, S. Benedikt, I. Sax, Sebastian Dintner, M. Eberle, A. Langer, Bruno M?rkl, S. Hummler, Matthias Schlesner, Boris Kubuschok, Martin Trepel and Rainer Claus. 2023. P703 Assessment of genetic tumor profiles and clonal evolution by liquid biopsy: the Augsburg Longitudinal Plasma Study (ALPS) [Abstract]. Oncology Research and Treatment 46, Supplement 5, 246. DOI: 10.1159/000533576
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Teng-Feng Li, Paul Rothhaar, Arthur Lang, Oliver Grünvogel, Ombretta Colasanti, Santa Mariela Olivera Ugarte, Jannik Traut, Antonio Piras, Nelson Acosta-Rivero, Vladimir Gon?alves Magalh?es, Emely Springer, Andreas Betz, Hao-En Huang, Jeongbin Park, Ruiyue Qiu, Gnimah Eva Gnouamozi, Ann-Kathrin Mehnert, Viet Loan Dao Thi, Stephan Urban, Martina Muckenthaler, Matthias Schlesner, Dirk Wohlleber, Marco Binder, Ralf Bartenschlager, Andreas Pichlmair and Volker Lohmann. in press. RBM39 shapes innate immunity through transcriptional and splicing control of key factors of the interferon response. preprint. DOI: 10.1101/2023.10.13.562221
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Verena Turco, Kira Pfleiderer, Jessica Hunger, Natalie K. Horvat, Kianush Karimian-Jazi, Katharina Schregel, Manuel Fischer, Gianluca Brugnara, Kristine J?hne, Volker Sturm, Yannik Streibel, Duy Nguyen, Sandro Altamura, Dennis A. Agardy, Shreya S. Soni, Abdulrahman Alsasa, Theresa Bunse, Matthias Schlesner, Martina U. Muckenthaler, Ralph Weissleder, Wolfgang Wick, Sabine Heiland, Philipp Vollmuth, Martin Bendszus, Christopher B. Rodell, Michael O. Breckwoldt and Michael Platten. 2023. T cell-independent eradication of experimental glioma by intravenous TLR7/8-agonist-loaded nanoparticles. Nature Communications 14, 1, 771. DOI: 10.1038/s41467-023-36321-6
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Lars Buschhorn, Dorett I. Odoni, Johanna Geuder, Timo O. Odinius, Celina V. Wagner, Stefanie Jilg, Ulrike H?ckendorf, Adam Wahida, Matthias Schlesner, Andreas Reiter, Mohamad Jawhar and Philipp J. Jost. 2023. Transcriptomic profiling does not refine mastocytosis diagnosis. Haematologica 108, 11, 3125-3130. DOI: 10.3324/haematol.2022.282617
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Dieter Weichenhan, Anna Riedel, Charlotte Meinen, Alisa Basic, Reka Toth, Marion B?hr, Pavlo Lutsik, Joschka Hey, Etienne Sollier, Umut H. Toprak, Simge Kelek?i, Yu-Yu Lin, Mariam Hakobyan, Aurore Touzart, Ashish Goyal, Justyna A. Wierzbinska, Matthias Schlesner, Frank Westermann, Daniel B. Lipka and Christoph Plass. 2023. Translocation t(6;7) in AML-M4 cell line GDM-1 results in MNX1 activation through enhancer-hijacking. Leukemia 37, 5, 1147-1150. DOI: 10.1038/s41375-023-01865-5
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Enrique Blanco-Carmona, Ashwin Narayanan, Inmaculada Hernandez, Juan C. Nieto, Marc Elosua-Bayes, Xueyuan Sun, Claudia Schmidt, Necmettin Pamir, Koray ?zduman, Christel Herold-Mende, Francesca Pagani, Manuela Cominelli, Julian Taranda, Wolfgang Wick, Andreas von Deimling, Pietro Luigi Poliani, Michael Rehli, Matthias Schlesner, Holger Heyn and ?evin Turcan. 2023. Tumor heterogeneity and tumor-microglia interactions in primary and recurrent IDH1-mutant gliomas. Cell Reports 伟德国际_伟德国际1946$娱乐app游戏icine 4, 11, 101249. DOI: 10.1016/j.xcrm.2023.101249
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M. Hartmann, M. Schonung, J. Rajak, J. Hey, V. Maurer, L. Hai, S. Staeble, J. Langstein, K. Bauer, M. Hakobyan, L. Jardine, S. Bohler, D. Vonficht, A. H. Maag, D. Lebrecht, K. M. Bernt, R. Roelz, T. Boch, E. Khabirova, P. Lutsik, S. Haas, A. M. Hani, S. Behjati, J.-P. Mallm, C. Buske, M. D. Milsom, S. Frohling, M.-J. Bonder, C. Niemeyer, C. Flotho, C. Plass, M. Erlacher, Matthias Schlesner and D. B. Lipka. 2023. V849 Onco-fetal reprogramming in juvenile myelomonocytic leukemia upregulates surface markers which can be exploited as therapeutic targets [Abstract]. Oncology Research and Treatment 46, Supplement 5, 119. DOI: 10.1159/000533576
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Mikael Beyene, Philipp A. Toussaint, Scott Thiebes, Matthias Schlesner, Benedikt Brors and Ali Sunyaev. 2022. A scoping review of distributed ledger technology in genomics: thematic analysis and directions for future research. Journal of the American 伟德国际_伟德国际1946$娱乐app游戏ical Informatics Association 29, 8, 1433-1444. DOI: 10.1093/jamia/ocac077
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David Hausmann, Dirk C. Hoffmann, Varun Venkataramani, Erik Jung, Sandra Horschitz, Svenja K. Tetzlaff, Ammar Jabali, Ling Hai, Tobias Kessler, Daniel D. Azo?in, Sophie Weil, Alexandros Kourtesakis, Philipp Sievers, Antje Habel, Michael O. Breckwoldt, Matthia A. Karreman, Miriam Ratliff, Julia M. Messmer, Yvonne Yang, Ekin Reyhan, Susann Wendler, Cathrin L?b, Chanté Mayer, Katherine Figarella, Matthias Osswald, Gergely Solecki, Felix Sahm, Olga Garaschuk, Thomas Kuner, Philipp Koch, Matthias Schlesner, Wolfgang Wick and Frank Winkler. 2022. Autonomous rhythmic activity in glioma networks drives brain tumour growth. Nature 613, 7942, 179-186. DOI: 10.1038/s41586-022-05520-4
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Nicola Giesen, Nagarajan Paramasivam, Umut H. Toprak, Daniel Huebschmann, Jing Xu, Sebastian Uhrig, Mehmet Samur, Stella B?hr, Martina Fr?hlich, Sadaf S. Mughal, Elias K. Mai, Anna Jauch, Carsten Müller-Tidow, Benedikt Brors, Nikhil Munshi, Hartmut Goldschmidt, Niels Weinhold, Matthias Schlesner and Marc S. Raab. 2022. Comprehensive genomic analysis of refractory multiple myeloma reveals a complex mutational landscape associated with drug resistance and novel therapeutic vulnerabilities. Haematologica 107, 8, 1891-1901. DOI: 10.3324/haematol.2021.279360
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Melinda Czeh, Sina St?ble, Stephen Kr?mer, Lena Tepe, Sweta Talyan, Joana Carrelha, Yiran Meng, Barbara Heitplatz, Marius Schwabenland, Michael D. Milsom, Christoph Plass, Marco Prinz, Matthias Schlesner, Miguel A. Andrade-Navarro, Claus Nerlov, Sten Eirik W. Jacobsen, Daniel B. Lipka and Frank Rosenbauer. 2022. DNMT1 deficiency impacts on plasmacytoid dendritic cells in homeostasis and autoimmune disease. The Journal of Immunology 208, 2, 358-370. DOI: 10.4049/jimmunol.2100624
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Marina Laplana, Matthias Bieg, Christian Faltus, Svitlana Melnik, Olga Bogatyrova, Zuguang Gu, Thomas Muley, Michael Meister, Hendrik Dienemann, Esther Herpel, Christopher I. Amos, Matthias Schlesner, Roland Eils, Christoph Plass and Angela Risch. 2022. Differentially methylated regions within lung cancer risk loci are enriched in deregulated enhancers. Epigenetics 17, 2, 117-132. DOI: 10.1080/15592294.2021.1878723
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Heike Peterziel, Nora Jamaladdin, Dina ElHarouni, Xenia F. Gerloff, Sonja Herter, Petra Fiesel, Yannick Berker, Mirjam Blattner-Johnson, Kathrin Schramm, Barbara C. Jones, David Reuss, Laura Turunen, Aileen Friedenauer, Tim Holland-Letz, Martin Sill, Lena Weiser, Christopher Previti, Gnanaprakash Balasubramanian, Nicolas U. Gerber, Johannes Gojo, Caroline Hutter, Ingrid ?ra, Olli Lohi, Antonis Kattamis, Bram de Wilde, Frank Westermann, Stephan Tippelt, Norbert Graf, Michaela Nathrath, Monika Sparber-Sauer, Astrid Sehested, Christof M. Kramm, Uta Dirksen, Olli Kallioniemi, Stefan M. Pfister, Cornelis M. van Tilburg, David T. W. Jones, Jani Saarela, Vilja Pieti?inen, Natalie J?ger, Matthias Schlesner, Annette Kopp-Schneider, Sina Oppermann, Till Milde, Olaf Witt and Ina Oehme. 2022. Drug sensitivity profiling of 3D tumor tissue cultures in the pediatric precision oncology program INFORM. npj Precision Oncology 6, 1, 94. DOI: 10.1038/s41698-022-00335-y
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Paurnima Patil, Umut H. Toprak, Julian Seufert, Till Braun, Stephan H. Bernhart, Laura Wiehle, Annika Müller, Matthias Schlesner, Marco Herling, Peter Lichter, Stephan Stilgenbauer, Reiner Siebert and Marc Zapatka. 2022. Exploration of whole genome and transcriptome sequencing data lacks evidence for oncogenic viral elements to drive the pathogenesis of T-cell prolymphocytic leukemia. Leukemia and Lymphoma 63, 13, 3253-3256. DOI: 10.1080/10428194.2022.2116933
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Cristina Lopez, Nikolai Schleussner, Stephan H. Bernhart, Kortine Kleinheinz, Stephanie Sungalee, Henrike L. Sczakiel, Helene Kretzmer, Umut H. Toprak, Selina Glaser, Rabea Wagener, Ole Ammerpohl, Susanne Bens, Maciej Giefing, Juan C. Gonzalez Sanchez, Gordana Apic, Daniel Hubschmann, Martin Janz, Markus Kreuz, Anja Mottok, Judith M. Muller, Julian Seufert, Steve Hoffmann, Jan O. Korbel, Robert B. Russell, Roland Schule, Lorenz Trumper, Wolfram Klapper, Bernhard Radlwimmer, Peter Lichter, Ralf Kuppers, Matthias Schlesner, Stephan Mathas and Reiner Siebert. 2022. Focal structural variants revealed by whole genome sequencing disrupt the histone demethylase KDM4C in B cell lymphomas. Haematologica 108, 2, 543-554. DOI: 10.3324/haematol.2021.280005
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Lizhen Zhu, Beiping Miao, Dagmara Dymerska, Magdalena Kuswik, Elena Bueno-Martínez, Lara Sanoguera-Miralles, Eladio A. Velasco, Nagarajan Paramasivam, Matthias Schlesner, Abhishek Kumar, Ying Yuan, Jan Lubinski, Obul Reddy Bandapalli, Kari Hemminki and Asta F?rsti. 2022. Germline variants of CYBA and TRPM4 predispose to familial colorectal cancer. Cancers 14, 3, 670. DOI: 10.3390/cancers14030670
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Weiyin Zhou, Anja Pfaus, Martin Ogwang, Wen Luo, Patrick Kerchan, Steven Reynolds, Constance N. Tenge, Pamela A. Were, Robert T. Kuremu, Walter N. Wekesa, Nestory Masalu, Esther Kawira, Tobias Kinyera, Isaac Otim, Ismail D. Legason, Hadijah Nabalende, Leona W. Ayers, Kishor Bhatia, James J. G?dert, Nathan Cole, Belynda Hicks, Kristine Jones, Michael Hummel, Matthias Schlesner, George Chagaluka, Nora Mutalima, Eric Borgstein, George N. Liomba, Steve Kamiza, Nyengo Mkandawire, Collins Mitambo, Elizabeth Molyneux, Robert Newton, Selina Glaser, Michelle Manning, Amy Hutchinson, Ann W. Hsing, Yao Tettey, Andrew Anthony Adjei, Stephen J. Chanock, Reiner Siebert, Meredith Yeager, Mitchell Machiela and Sam M. Mbulaiteye. 2022. Increased frequency of mosaic chromosomal alterations in peripheral blood samples of Sub-Saharan African children with endemic Burkitt lymphoma [Abstract]. Blood 140, Supplement 1, 9240-9241. DOI: 10.1182/blood-2022-169500
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Ruzhica Bogeska, Ana-Matea Mikecin, Paul Kaschutnig, Malak Fawaz, Marleen Büchler-Sch?ff, Duy Le, Miguel Ganuza, Angelika Vollmer, Stella V. Paffenholz, Noboru Asada, Esther Rodriguez-Correa, Felix Frauhammer, Florian Buettner, Melanie Ball, Julia Knoch, Sina St?ble, Dagmar Walter, Amelie Petri, Martha J. Carre?o-Gonzalez, Vinona Wagner, Benedikt Brors, Simon Haas, Daniel B. Lipka, Marieke A.G. Essers, Vivienn Weru, Tim Holland-Letz, Jan-Philipp Mallm, Karsten Rippe, Stephan Kr?mer, Matthias Schlesner, Shannon McKinney Freeman, Maria Carolina Florian, Katherine Y. King, Paul S. Frenette, Michael A. Rieger and Michael D. Milsom. 2022. Inflammatory exposure drives long-lived impairment of hematopoietic stem cell self-renewal activity and accelerated aging. Cell Stem Cell 29, 8, 1273-1284.e8. DOI: 10.1016/j.stem.2022.06.012
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Hamed Alborzinia, Andrés F. Flórez, Sina Kreth, Lena M. Brückner, Umut Yildiz, Moritz Gartlgruber, Dorett I. Odoni, Gernot Poschet, Karolina Garbowicz, Chunxuan Shao, Corinna Klein, Jasmin Meier, Petra Zeisberger, Michal Nadler-Holly, Matthias Ziehm, Franziska Paul, Jürgen Burhenne, Emma Bell, Marjan Shaikhkarami, Roberto Würth, Sabine A. Stainczyk, Elisa M. Wecht, Jochen Kreth, Michael Büttner, Naveed Ishaque, Matthias Schlesner, Barbara Nicke, Carlo Stresemann, María Llamazares-Prada, Jan H. Reiling, Matthias Fischer, Ido Amit, Matthias Selbach, Carl Herrmann, Stefan W?lfl, Kai-Oliver Henrich, Thomas H?fer, Andreas Trumpp and Frank Westermann. 2022. MYCN mediates cysteine addiction and sensitizes neuroblastoma to ferroptosis. Nature Cancer 3, 4, 471-485. DOI: 10.1038/s43018-022-00355-4
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Mark Hartmann, Ling Hai, Joschka Hey, Maximilian Sch?nung, Valentin Maurer, Jovana Rajak, Sina St?ble, Jens Langstein, Katharina Bauer, Mariam Hakobyan, Laura Jardine, Sheila Bohler, Dominik Vonficht, Abdul-Habib Maag, Dirk Lebrecht, Kathrin M. Bernt, Roland R?lz, Tobias Boch, Eleonora Khabirova, Pavlo Lutsik, Oliver Stegle, Simon Haas, Muzlifah Haniffa, Sam Behjati, Jan-Philipp Mallm, Christian Buske, Stefan Fr?hling, Christoph Plass, Charlotte M. Niemeyer, Christian Flotho, Marc Jan Bonder, Miriam Erlacher, Matthias Schlesner and Daniel B. Lipka. 2022. Multi-omics profiling of JMML HSPCs reveals onco-fetal reprogramming and identifies novel prognostic biomarkers and therapeutic targets in high-risk JMML [Abstract]. Blood 140, Supplement 1, 8729-8730. DOI: 10.1182/blood-2022-162224
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Dina ElHarouni, Heike Peterziel, Kathrin Schramm, Till Milde, Sina Oppermann, Ina ?hme, Olaf Witt, Matthias Schlesner and Natalie Jager. 2022. Multiomics analysis of pediatric solid tumors within the INFORM precision oncology study: from functional drug profiling to biomarker identification [Abstract]. Journal of Clinical Oncology 40, 16, Supplement S, 10036.
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Yannick Berker, Dina ElHarouni, Heike Peterziel, Petra Fiesel, Olaf Witt, Ina Oehme, Matthias Schlesner and Sina Oppermann. 2022. Patient-by-patient deep transfer learning for drug-response profiling using confocal fluorescence microscopy of pediatric patient-derived tumor-cell spheroids. IEEE Transactions on 伟德国际_伟德国际1946$娱乐app游戏ical Imaging 41, 12, 3981-3999. DOI: 10.1109/tmi.2022.3205554
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Corinne Hübers, Ashik Ahmed Abdul Pari, Denise Grieshober, Martin Petkov, Alexander Schmidt, Tatjana Messmer, Christian Moritz Heyer, Sebastian Sch?lch, Stephanie S. Kapel, Nicolas Gengenbacher, Mahak Singhal, Benjamin Schieb, Claudine Fricke, Rainer Will, Kim Remans, Jochen Sven Utikal, Christoph Reissfelder, Matthias Schlesner, Kairbaan M. Hodivala-Dilke, Sander Kersten, Sergij Goerdt, Hellmut G. Augustin and Moritz Felcht. 2022. Primary tumor–derived systemic nANGPTL4 inhibits metastasis. Journal of Experimental 伟德国际_伟德国际1946$娱乐app游戏icine 220, 1, e20202595. DOI: 10.1084/jem.20202595
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Areeba Patel, Helin Dogan, Alexander Payne, Elena Krause, Philipp Sievers, Natalie Schoebe, Daniel Schrimpf, Christina Blume, Damian Stichel, Nadine Holmes, Philipp Euskirchen, Jürgen Hench, Stephan Frank, Violaine Rosenstiel-Goidts, Miriam Ratliff, Nima Etminan, Andreas Unterberg, Christoph Dieterich, Christel Herold-Mende, Stefan M. Pfister, Wolfgang Wick, Matthew Loose, Andreas von Deimling, Martin Sill, David T. W. Jones, Matthias Schlesner and Felix Sahm. 2022. Rapid-CNS2: rapid comprehensive adaptive nanopore-sequencing of CNS tumors, a proof-of-concept study. Acta Neuropathologica 143, 5, 609-612. DOI: 10.1007/s00401-022-02415-6
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Josefine Radke, Naveed Ishaque, Randi Koll, Zuguang Gu, Elisa Schumann, Lina Sieverling, Sebastian Uhrig, Daniel Hübschmann, Umut H. Toprak, Cristina López, Xavier Pastor Hostench, Simone Borgoni, Dilafruz Juraeva, Fabienne Pritsch, Nagarajan Paramasivam, Gnana Prakash Balasubramanian, Matthias Schlesner, Shashwat Sahay, Marc Weniger, Debora Pehl, Helena Radbruch, Anja Osterloh, Agnieszka Korfel, Martin Misch, Julia Onken, Katharina Faust, Peter Vajkoczy, Dag Moskopp, Yawen Wang, Andreas J?dicke, Lorenz Trümper, Ioannis Anagnostopoulos, Dido Lenze, Ralf Küppers, Michael Hummel, Clemens A. Schmitt, Otmar D. Wiestler, Stephan Wolf, Andreas Unterberg, Roland Eils, Christel Herold-Mende, Benedikt Brors, Reiner Siebert, Stefan Wiemann and Frank L. Heppner. 2022. The genomic and transcriptional landscape of primary central nervous system lymphoma. Nature Communications 13, 1, 2558. DOI: 10.1038/s41467-022-30050-y
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Paurnima Patil, Sina Hillebrecht, Emil Chteinberg, Cristina López, Umut H. Toprak, Julian Seufert, Stephan H. Bernhart, Helene Kretzmer, Anke K. Bergmann, Susanne Bens, Josef H?gel, Annika Müller, Billy Michael Jebaraj, Alexandra Schrader, Patricia Johansson, Dolors Costa, Matthias Schlesner, Jan Dürig, Marco Herling, Elias Campo, Stephan Stilgenbauer, Laura Wiehle and Reiner Siebert. 2022. T‐cell prolymphocytic leukemia is associated with deregulation of oncogenic microRNAs on transcriptional and epigenetic level. Genes, Chromosomes and Cancer 61, 7, 432-436. DOI: 10.1002/gcc.23034
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Diamanto Skopelitou, Aayushi Srivastava, Beiping Miao, Abhishek Kumar, Dagmara Dymerska, Nagarajan Paramasivam, Matthias Schlesner, Jan Lubinski, Kari Hemminki, Asta F?rsti and Obul Reddy Bandapalli. 2022. Whole exome sequencing identifies novel germline variants of SLC15A4 gene as potentially cancer predisposing in familial colorectal cancer. Molecular Genetics and Genomics 297, 4, 965-979. DOI: 10.1007/s00438-022-01896-0
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Beiping Miao, Diamanto Skopelitou, Aayushi Srivastava, Sara Giangiobbe, Dagmara Dymerska, Nagarajan Paramasivam, Abhishek Kumar, Magdalena Ku?wik, Wojciech Klu?niak, Katarzyna Paszkowska-Szczur, Matthias Schlesner, Jan Lubinski, Kari Hemminki, Asta F?rsti and Obul Reddy Bandapalli. 2022. Whole-exome sequencing identifies a novel germline variant in PTK7 gene in familial colorectal cancer. International Journal of Molecular Sciences 23, 3, 1295. DOI: 10.3390/ijms23031295
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Dina ElHarouni, Yannick Berker, Heike Peterziel, Apurva Gopisetty, Laura Turunen, Sina Kreth, Sabine A. Stainczyk, Ina Oehme, Vilja Pieti?inen, Natalie J?ger, Olaf Witt, Matthias Schlesner and Sina Oppermann. 2022. iTReX: Interactive exploration of mono- and combination therapy dose response profiling data. Pharmacological Research 175, 105996. DOI: 10.1016/j.phrs.2021.105996
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Diamanto Skopelitou, Beiping Miao, Aayushi Srivastava, Abhishek Kumar, Magdalena Ku?wik, Dagmara Dymerska, Nagarajan Paramasivam, Matthias Schlesner, Jan Lubiński, Kari Hemminki, Asta F?rsti and Obul Reddy Bandapalli. 2021. A novel low-risk germline variant in the SH2 domain of the SRC gene affects multiple pathways in familial colorectal cancer. Journal of Personalized 伟德国际_伟德国际1946$娱乐app游戏icine 11, 4, 262. DOI: 10.3390/jpm11040262
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Abhishek Kumar, Nagarajan Paramasivam, Obul Reddy Bandapalli, Matthias Schlesner, Tianhui Chen, Rolf Sijmons, Dagmara Dymerska, Katarzyna Golebiewska, Magdalena Kuswik, Jan Lubinski, Kari Hemminki and Asta F?rsti. 2021. A rare large duplication of MLH1 identified in Lynch syndrome. Hereditary Cancer in Clinical Practice 19, 1, 10. DOI: 10.1186/s13053-021-00167-0
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Elisa Espinet, Zuguang Gu, Charles D. Imbusch, Nathalia A. Giese, Magdalena Büscher, Mariam Safavi, Silke Weisenburger, Corinna Klein, Vanessa Vogel, Mattia Falcone, Jacob Insua-Rodríguez, Manuel Reitberger, Vera Thiel, Steffi O. Kossi, Alexander Muckenhuber, Karnjit Sarai, Alex Y. L. Lee, Elyne Backx, Soheila Zarei, Matthias M. Gaida, Manuel Rodríguez-Paredes, Elisa Donato, Hsi-Yu Yen, Roland Eils, Matthias Schlesner, Nicole Pfarr, Thilo Hackert, Christoph Plass, Benedikt Brors, Katja Steiger, Dieter Weichenhan, H. Efsun Arda, Ilse Rooman, Janel L. Kopp, Oliver Strobel, Wilko Weichert, Martin R. Sprick and Andreas Trumpp. 2021. Aggressive PDACs show hypomethylation of repetitive elements and the execution of an intrinsic IFN program linked to a ductal cell of origin. Cancer Discovery 11, 3, 638-659. DOI: 10.1158/2159-8290.cd-20-1202
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Jeongbin Park, Wonyl Choi, Sebastian Tiesmeyer, Brian Long, Lars E. Borm, Emma Garren, Thuc Nghi Nguyen, Bosiljka Tasic, Simone Codeluppi, Tobias Graf, Matthias Schlesner, Oliver Stegle, Roland Eils and Naveed Ishaque. 2021. Cell segmentation-free inference of cell types from in situ transcriptomics data. Nature Communications 12, 1, 3545. DOI: 10.1038/s41467-021-23807-4