Publikationen PD. Dr. Johannes D?scher
2024
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2023
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2022
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2021
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2020
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2019
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2018
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2017
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2016
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2015
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2014
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2024 |
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Laban S., Remark R., Idel C., Ribbat-Idel J., Krupar R., Schr?ck A., Klümper N., D?scher Johannes, Sikora A. G., Abou Kors T., von Witzleben A., Vahl J., Grages A., Sonntag M., Brunner C., Hoffmann T. K., Gnjatic S..
915P Longer OS and RFS for CD3high/PD-L1+ head and neck squamous cell carcinoma (HNSCC) patients [Abstract].
https://doi.org/10.1016/j.annonc.2024.08.976
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D?scher Johannes, Emmanuel Benjamin, Greve Jens, Schuler Patrick J., Sommer Fabian, Laban Simon, Veit Johannes, Hoffmann Thomas K..
Barbed suture in neck dissection: a randomized clinical study on efficacy, safety and aesthetic outcome.
https://doi.org/10.1007/s00405-024-08869-6
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Burggraf Manuela, Schiele Stefan, Th?lken Rubens, Farfán López Francisco José, Elawany Noran, Zenk Johannes, Doescher Johannes.
Contemporary treatment and outcome of sinonasal undifferentiated carcinoma: a meta-analysis.
https://doi.org/10.1002/hed.27910
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D?scher Johannes, Zenk Johannes.
HNO-Erkrankungsbilder.
https://doi.org/10.1016/b978-3-437-21442-4.00027-9
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von Witzleben Adrian, Grages Ayla, Thomas Jaya, Ezi? Jasmin, Brunner Cornelia, Schuler Patrick J., Kraus Johann M., Kestler Hans A., Vahl Julius M., Doescher Johannes, King Emma V., Ottensmeier Christian H., Hoffmann Thomas K., Laban Simon.
Immune checkpoint expression on tumor-infiltrating lymphocytes (TIL) is dependent on HPV status in oropharyngeal carcinoma (OPSCC) – a single-cell RNA sequencing analysis.
https://doi.org/10.1016/j.oraloncology.2024.107107
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von Witzleben Adrian, Doescher Johannes, Hoffmann Thomas K., Laban Simon.
Immuntherapie von Kopf-Hals-Tumoren: Neuigkeiten von der ASCO-Jahresversammlung 2024.
https://doi.org/10.1007/s00106-024-01524-w
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Abou Kors Tsima, Meier Matthias, Mühlenbruch Lena, Betzler Annika C., Oliveri Franziska, Bens Martin, Thomas Jaya, Kraus Johann M., D?scher Johannes, von Witzleben Adrian, Hofmann Linda, Ezic Jasmin, Huber Diana, Benckendorff Julian, Barth Thomas F. E., Greve Jens, Schuler Patrick J., Brunner Cornelia, Blackburn Jonathan M., Hoffmann Thomas K., Ottensmeier Christian, Kestler Hans A., Rammensee Hans-Georg, Walz Juliane S., Laban Simon.
Multi-omics analysis of overexpressed tumor-associated proteins: gene expression, immunopeptide presentation, and antibody response in oropharyngeal squamous cell carcinoma, with a focus on cancer-testis antigens.
https://doi.org/10.3389/fimmu.2024.1408173
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Cidlinsky Natascha, Arndt Tim Tobias, Schiele Stefan, Th?lken Rubens, Treutlein Eric, Müller Gernot, Zenk Johannes, Doescher Johannes.
Therapeutic management of peritonsillar abscess during COVID-19.
https://doi.org/10.1007/s00405-024-08772-0
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Sharma S. J., Klussmann J. P., D?scher Johannes, Hoffmann T. K., Laban S..
Update zu HPV-assoziierten Kopf-Hals-Karzinomen?– Highlights der ASCO-Jahrestagung 2024.
https://doi.org/10.1007/s00106-024-01525-9
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2023 |
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Betzler Annika C., Strobel Hannah, Abou Kors Tsima, Ezi? Jasmin, Lesakova Kristina, Pscheid Ronja, Azoitei Ninel, Sporleder Johanna, Staufenberg Anna-Rebekka, Drees Robert, Weissinger Stephanie E., Greve Jens, Doescher Johannes, Theodoraki Marie-Nicole, Schuler Patrick J., Laban Simon, Kibe Toshiro, Kishida Michiko, Kishida Shosei, Idel Christian, Hoffmann Thomas K., Lavitrano Marialuisa, Grassilli Emanuela, Brunner Cornelia.
BTK isoforms p80 and p65 are expressed in head and neck squamous cell carcinoma (HNSCC) and involved in tumor progression.
https://doi.org/10.3390/cancers15010310
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Vahl Julius, Weissinger Stephanie, Welke Claudia, Hoffmann Thomas, D?scher Johannes.
Chemokine receptor expression in squamous cell - and adeno-subtypes of sinonasal carcinoma.
https://doi.org/10.21608/ejentas.2023.194914.1612
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Choi Ying-Chu, Chan Po-Chung, Cheung Ka-Wai Alice, Huang Jia-Jie, Wong Kwok-Leung Aray, D?scher Johannes, Lam Tai-Chung.
Impact of weight loss on treatment interruption and unplanned hospital admission in head and neck cancer patients undergoing curative (chemo)-radiotherapy in Hong Kong.
https://doi.org/10.1007/s00520-023-07952-8
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Mühlenbruch Lena, Abou-Kors Tsima, Dubbelaar Marissa L., Bichmann Leon, Kohlbacher Oliver, Bens Martin, Thomas Jaya, Ezi? Jasmin, Kraus Johann M., Kestler Hans A., von Witzleben Adrian, Mytilineos Joannis, Fürst Daniel, Engelhardt Daphne, D?scher Johannes, Greve Jens, Schuler Patrick J., Theodoraki Marie-Nicole, Brunner Cornelia, Hoffmann Thomas K., Rammensee Hans-Georg, Walz Juliane S., Laban Simon.
The HLA ligandome of oropharyngeal squamous cell carcinomas reveals shared tumour-exclusive peptides for semi-personalised vaccination.
https://doi.org/10.1038/s41416-023-02197-y
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D?scher Johannes, Zenk Johannes.
Vorbereitung zur Facharztprüfung?HNO: Folge 65.
https://doi.org/10.1007/s00106-023-01277-y
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2022 |
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Doescher Johannes, von Witzleben Adrian, Boukas Konstantinos, Weissinger Stephanie E., Thomas Gareth J., Laban Simon, Thomas Jaya, Hoffmann Thomas K., Ottensmeier Christian H..
Changes in gene expression patterns in the tumor microenvironment of head and neck squamous cell carcinoma under chemoradiotherapy depend on response.
https://doi.org/10.3389/fonc.2022.862694
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Jonas Hanna, Simnica Donjete, Bu?mann Lara, Zech Henrike, Doescher Johannes, Laban Simon, Busch Chia-Jung, Binder Mascha.
Early relapse detection by monitoring of circulating cell-free DNA in patients with localized head and neck squamous cell carcinoma: a subgroup analysis of the multicenter randomized clinical trial IMSTAR-HN [Letter].
https://doi.org/10.1016/j.oraloncology.2022.105733
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Goldberg‐Bockhorn Eva, Wenzel Ulla, Theodoraki Marie‐Nicole, D?scher Johannes, Riepl Ricarda, Wigand Marlene C., Brunner Cornelia, He?ling Martin, Hoffmann Thomas K., Kern Johann, Rotter Nicole.
Enhanced cellular migration and prolonged chondrogenic differentiation in decellularized cartilage scaffolds under dynamic culture conditions.
https://doi.org/10.1002/term.3261
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Beck M., Hartwich J., Eckstein M., Schmidt D., Gostian A. O., Müller S., Rutzner S., Gaipl U. S., von der Grün J., Illmer T., Hautmann M. G., Klautke G., D?scher Johannes, Brunner T., Tamaskovics B., Hartmann A., Iro H., Kuwert T., Fietkau R., Hecht M., Semrau S..
F18-FDG PET/CT imaging early predicts pathologic complete response to induction chemoimmunotherapy of locally advanced head and neck cancer: preliminary single-center analysis of the checkrad-cd8 trial.
https://doi.org/10.1007/s12149-022-01744-6
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Doescher Johannes, Meyer Moritz, Arolt Christoph, Quaas Alexander, Klu?mann Jens Peter, Wolber Philipp, Bankfalvi Agnes, Schildhaus Hans-Ulrich, Bastian Tobias, Lang Stephan, Laban Simon, Schuler Patrick J., Brunner Cornelia, Hoffmann Thomas K., Weissinger Stephanie E..
Patterns of tumor infiltrating lymphocytes in adenoid cystic carcinoma of the head and neck.
https://doi.org/10.3390/cancers14061383
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von Witzleben Adrian, Müller-Richter Urs, Maurus Katja, Br?ndlein Stephanie, Theodoraki Marie-Nicole, Brunner Cornelia, Laban Simon, Lennerz Jochen, M?ller Peter, Hoffmann Thomas K., Doescher Johannes, Schuler Patrick J..
Protein-based oncopanel as addition to target sequencing in head and neck squamous cell carcinoma to individualize treatment decisions.
https://doi.org/10.3390/ijms232415835
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2021 |
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Brand Matthias, Laban Simon, Theodoraki Marie-Nicole, Doescher Johannes, Hoffmann Thomas K., Schuler Patrick J., Brunner Cornelia.
Characterization and differentiation of the tumor microenvironment (TME) of orthotopic and subcutaneously grown head and neck squamous cell carcinoma (HNSCC) in immunocompetent mice.
https://doi.org/10.3390/ijms22010247
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Doescher Johannes, Ott S., K?vi J., Steinacker J., Hoffmann T. K., Sommer F..
Diagnostik und Therapie maligner Nasentumoren.
https://doi.org/10.1007/s11654-021-00323-x
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Doescher Johannes, Minkenberg Peter, Laban Simon, Kostezka Ulrike, Witzleben Adrian, Hoffmann Thomas Karl, Schuler Patrick Johannes, Weissinger Stephanie Ellen.
Immune checkpoint expression in HNSCC patients before and after definitive chemoradiotherapy.
https://doi.org/10.1002/hed.26534
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Vahl Julius M., Wigand Marlene C., Denkinger Michael, Dallmeier Dhayana, Steiger Chiara, Welke Claudia, Kuhn Peter, Idel Christian, Doescher Johannes, von Witzleben Adrian, Brand Matthias, Marienfeld Ralf, M?ller Peter, Theodoraki Marie-Nicole, Greve Jens, Schuler Patrick J., Brunner Cornelia, Hoffmann Thomas K., Laban Simon.
Increasing mean age of head and neck cancer patients at a German tertiary referral center.
https://doi.org/10.3390/cancers13040832
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Vahl J. M., von Witzleben A., Welke C., Doescher Johannes, Theodoraki M. N., Brand M., Schuler P. J., Greve J., Hoffmann T. K., Laban S..
Influence of travel burden on tumor classification and survival of head and neck cancer patients.
https://doi.org/10.1007/s00405-021-06816-3
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B?hm Felix, Schuler Patrick J., D?scher Johannes, Weissinger Stephanie E., Benckendorff Julian, Greve Jens, Hoffmann Thomas K., Theodoraki Marie-Nicole.
Kleinzelliges neuroendokrines Karzinom des Kopf-Hals-Bereichs: eine ?bersichtsarbeit und Fallserie.
https://doi.org/10.1055/a-1334-4444
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D?scher Johannes, Hoffmann Thomas K..
Kommentar zu "Leitlinie zur Behandlung der Kopf-Hals-Karzinome – ein kritischer Blick".
https://doi.org/10.1055/a-1623-6848
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Witzleben Adrian, Fehn Adrian, Grages Ayla, Ezi? Jasmin, Jeske Sandra S., Puntigam Lisa K., Brunner Cornelia, Kraus Johann M., Kestler Hans A., Doescher Johannes, Brand Matthias, Theodoraki Marie‐Nicole, Ottensmeier Christian H., Hoffmann Thomas K., Schuler Patrick J., Laban Simon.
Prospective longitudinal study of immune checkpoint molecule (ICM) expression in immune cell subsets during curative conventional therapy of head and neck squamous cell carcinoma (HNSCC).
https://doi.org/10.1002/ijc.33446
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Sieron Hannah Lara, Trainotti Susanne, Hoffmann Thomas, D?scher Johannes.
Tubenfunktionsst?rung bei aberrantem Verlauf der Tuba auditiva beidseits.
https://doi.org/10.1055/a-1475-5087
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Laban S., Brand M, Ezi? J., Doescher Johannes, V?lkel G., Kestler H. A., Brunner C., Hoffmann T. K..
Tumorbiologie des Oropharynxkarzinoms.
https://doi.org/10.1007/s00106-020-00964-4
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2020 |
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Wilkat Max, Bast Hanna, Drees Robert, Dünser Johannes, Mahr Amelie, Azoitei Ninel, Marienfeld Ralf, Frank Felicia, Brhel Magnus, Ushmorov Alexey, Greve Jens, Goldberg‐Bockhorn Eva, Theodoraki Marie‐Nicole, Doescher Johannes, Laban Simon, Schuler Patrick J., Hoffmann Thomas K., Brunner Cornelia.
Adenosine receptor 2B activity promotes autonomous growth, migration as well as vascularization of head and neck squamous cell carcinoma cells.
https://doi.org/10.1002/ijc.32835
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Jeske Sandra S., Brand Matthias, Ziebart Andreas, Laban Simon, Doescher Johannes, Greve Jens, Jackson Edwin K., Hoffmann Thomas K., Brunner Cornelia, Schuler Patrick J..
Adenosine-producing regulatory B cells in head and neck cancer.
https://doi.org/10.1007/s00262-020-02535-6
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Jeske S. S., Schuler P. J., Doescher Johannes, Theodoraki M. N., Laban S., Brunner C., Hoffmann T. K., Wigand M. C..
Age-related changes in T lymphocytes of patients with head and neck squamous cell carcinoma.
https://doi.org/10.1186/s12979-020-0174-7
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Doescher Johannes, Brand M., Hoffmann Thomas K..
Aktuelle Therapieaspekte des Plattenepithelkarzinoms im Kopf-Hals-Bereich.
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Dahlhaus Meike, Roos Julian, Engel Daniel, Tews Daniel, Halbgebauer Daniel, Funcke Jan-Bernd, Kiener Sophie, Schuler Patrick J., D?scher Johannes, Hoffmann Thomas K., Zinngrebe Julia, Rojewski Markus, Schrezenmeier Hubert, Debatin Klaus-Michael, Wabitsch Martin, Fischer-Posovszky Pamela.
CD90 is dispensable for white and beige/brown adipocyte differentiation.
https://doi.org/10.3390/ijms21217907
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Schroeder Jan C., Puntigam Lisa, Hofmann Linda, Jeske Sandra S., Beccard Inga J., Doescher Johannes, Laban Simon, Hoffmann Thomas K., Brunner Cornelia, Theodoraki Marie-Nicole, Schuler Patrick J..
Circulating exosomes inhibit B cell proliferation and activity.
https://doi.org/10.3390/cancers12082110
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Meyer M. F., Arolt C., Kansy B. A., Doescher Johannes, Quaas A., Beutner D., Lang S., Klu?mann J. P..
Das Tumormikromilieu bei Speicheldrüsenkarzinomen – m?gliche Konsequenzen für neue Therapiekonzepte.
https://doi.org/10.1007/s00106-020-00926-w
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Puntigam Lisa K., Jeske Sandra S., G?tz Marlies, Greiner Jochen, Laban Simon, Theodoraki Marie-Nicole, Doescher Johannes, Weissinger Stephanie E., Brunner Cornelia, Hoffmann Thomas K., Schuler Patrick J..
Immune checkpoint expression on immune cells of HNSCC patients and modulation by chemo- and immunotherapy.
https://doi.org/10.3390/ijms21155181
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Betzler Annika C., Theodoraki Marie-Nicole, Schuler Patrick J., D?scher Johannes, Laban Simon, Hoffmann Thomas K., Brunner Cornelia.
NF-κB and its role in checkpoint control.
https://doi.org/10.3390/ijms21113949
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Wigand M. C., Jeske S., Hahn J., Doescher Johannes, Laban S., Hoffmann T. K., Schuler P. J..
Onkoimmunologie im Alter.
https://doi.org/10.1007/s00106-019-00758-3
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Mytilineos Daphne, Ezi? Jasmin, von Witzleben Adrian, Mytilineos Joannis, Lotfi Ramin, Fürst Daniel, Tsamadou Chrysanthi, Theodoraki Marie-Nicole, Oster Angelika, V?lkel Gunnar, Kestler Hans A., Brunner Cornelia, Schuler Patrick J., Doescher Johannes, Hoffmann Thomas K., Laban Simon.
Peripheral cytokine levels differ by HPV status and change treatment-dependently in patients with head and neck squamous cell carcinoma.
https://doi.org/10.3390/ijms21175990
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2019 |
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Laban Simon, Gangkofner Dominik S., Holzinger Dana, Schroeder Lea, Eichmüller Stefan B., Z?rnig Inka, J?ger Dirk, Wichmann Gunnar, Dietz Andreas, Broglie Martina A., Herold-Mende Christel C., Dyckhoff Gerhard, Boscolo-Rizzo Paolo, Ezi? Jasmin, Marienfeld Ralf, M?ller Peter, Kraus Johann M., V?lkel Gunnar, Kestler Hans A., Brunner Cornelia, Schuler Patrick J., Wigand Marlene C., Theodoraki Marie-Nicole, Doescher Johannes, Hoffmann Thomas K., Pawlita Michael, Waterboer Tim, Butt Julia.
Antibody responses to cancer antigens identify patients with a poor prognosis among HPV-positive and HPV-negative head and neck squamous cell carcinoma patients.
https://doi.org/10.1158/1078-0432.ccr-19-1490
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Doescher Johannes, Weissinger Stephanie E., Sch?nsteiner Stefan S., Lisson Catharina, Bullinger Lars, Barth Thomas F. E., Leith?user Frank, Mueller-Richter Urs, Laban Simon, Hoffmann Thomas K., M?ller Peter, Lennerz Jochen K., Schuler Patrick J..
Clinical utility of a protein-based oncopanel in patients with end-stage head and neck cancer.
https://doi.org/10.2217/imt-2019-0041
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Wuerdemann Nora, Doescher Johannes, Laban Simon, Hoffmann Thomas K., Klussmann Jens Peter.
Humane Papillomaviren und das Oropharynxkarzinom: frequently asked questions.
https://doi.org/10.1007/s00761-018-0519-4
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Doescher Johannes, Laban Simon, Schuler Patrick J., Brunner Cornelia, Hoffmann Thomas K..
Immunotherapy for head and neck cancers: an update and future perspectives.
https://doi.org/10.2217/imt-2019-0022
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Doescher Johannes, Busch C.-J., Wollenberg B., Dietz A., Würdemann N., Schuler P., Hoffmann T. K., Laban S..
Immuntherapie von Kopf-Hals-Tumoren: Highlights der ASCO-Jahrestagung 2019.
https://doi.org/10.1007/s00106-019-00761-8
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Sommer Fabian, Hoffmann Thomas Karl, Harter Lena, D?scher Johannes, Kleiner Sebastian, Lindemann J?rg, Leunig Andreas.
Incidence of anatomical variations according to the International Frontal Sinus Anatomy Classification (IFAC) and their coincidence with radiological sings of opacification.
https://doi.org/10.1007/s00405-019-05612-4
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Hagemann Jan, Roesner Jana, Helling Soenke, Jacobi Christian, Doescher Johannes, Engelbarts Matthias, Kuenzel Julian, Krauss Philipp, Becker Sven, Betz Christian Stephan.
Long‐term outcome for open and endoscopically resected sinonasal tumors.
https://doi.org/10.1177/0194599818815881
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