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BKH Augsburg
BKH Augsburg

RESEARCH

All the above-mentioned stimulation procedures are routinely offered in the treatment spectrum of out Clinic for Psychiatry, Psychotherapy and Psychosomatics. In addition, we offer scientific support as part of a professional team for both inpatients and outpatients. Currently, we focus on the treatment of people with depression or schizophrenic psychoses.

Current studies

cTBS-AH (TMS study in people with schizophrenia and persistent voice hearing)
In this study, TMS therapy is offered for the treatment of persistent acoustic hallucinations (especially persistent voice hearing). Due to a new form of TMS therapy (so-called theta burst stimulation, TBS), the duration of the individual treatments is less than 5 minutes, enabling as few stressful administrations as possible.?

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PREMISS?(TMS study in people with schizophrenia and negative symptoms)

In this project, TMS therapy is offered as part of an accompanying examination using magnetic resonance imaging (MRI) specifically for the treatment of negative symptoms. The MRI examinations determine markers that could be decisive for a good response to the therapy. In the future, MRI will be used to develop an individualised offer for patients as part of routine clinical applications.

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TBS-D?(TMS study in people with depression)

Within the scope of this study, the TMS therapy for the treatment of depressive disorders for patients who are not yet therapy-resistant (i.e., no more than 3 treatment attempts so far and a duration of the current episode of less than 2 years). Due to a new form of TMS therapy (so-called theta burst stimulation, TBS), the duration of the individual treatments with a few minutes enables as less stressful administration as possible. Stimulation of both frontal areas (alternating right and left) also offers a new, particularly effective application of TMS therapy for depression.

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ECT accompanying research and rTMS/TBS accompanying research

As part of our clinical applications, we repeatedly collect clinical data for the assessment of therapy responses by using questionnaires. A scientific evaluation and the development of individual treatment plans are offered to all our patients to improve their therapy.

(KEY-)PUBLICATIONS

  1. Papazova I,?Strube W, Wienert A, Henning B, Schwippel T, Fallgatter AJ, Padberg F, Falkai P, Plewnia C, Hasan A. Effects of 1 mA and 2 mA transcranial direct current stimulation on working memory performance in healthy participants. Conscious Cogn. 2020 Aug;83:102959. doi: 10.1016/j.concog.2020.102959. Epub 2020 Jun 2. PMID: 32502908.

  2. Haeckert J, Lasser C,?Pross B, Hasan A,?Strube W. Comparative study of motor cortical excitability changes following anodal tDCS or high-frequency tRNS in relation to stimulation duration. Physiol Rep. 2020 Oct;8(19):e14595. doi: 10.14814/phy2.14595. PMID: 32996722; PMCID: PMC7525483.

  3. G?gler N, Papazova I, Oviedo-Salcedo T, Filipova N,?Strube W, Funk J, Müller HJ, Finke K, Hasan A (2017) Parameter-Based Evaluation of Attentional Impairments in Schizophrenia and Their Modulation by Prefrontal Transcranial Direct Current Stimulation (tDCS). Front Psychiatry. 29;8:259.

  4. Strube W, Bunse T, Nitsche M, Palm U, Falkai P, Hasan A (2016) Differential response to anodal tDCS and PAS is indicative of impaired focal LTP-like plasticity in schizophrenia. Behavioral Brain Research (BBR), 311:46-53. doi: 10.1016/j.bbr.2016.05.027.

  5. Strube W, Bunse T, Nitsche MA, Nikolaeva A, Palm U, Padberg F, Falkai P, Hasan A (2016). Bidirectional variability in motor cortex excitability modulation following 1 mA transcranial direct current stimulation (tDCS) in healthy participants. Physiological Reports, 4(15). doi: 10.14814/phy2.12884.

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